PANACEA
Your travel can be customized according to your wishes.
Description
Dive into the beauty of Panama and the richness of its landscapes. Discover the most unforgettable places around the country.
The offer includes a personalized AZORA GUIDE with our best tricks & tips for every step of your travel.
Specifications
Duration
20 days/19 nights
Circuit price with bus transfers
From $3,170/pers.*
Circuit price with rental car
From $3,400/pers.*

Itinerary
Discover Panama and its wonderful landscapes with the PANACEA circuit.
Enjoy an authentic 20-day stay to discover the country’s most beautiful places.
Looking for specific information? Click directly on the title that interests you, and we’ll take you straight to what you’re looking for.

Details
Day 1:
Upon arrival at the Panama City airport, you will be met by our partner to take you to your hotel. Settle in comfortably and enjoy the streets of Panama City. Between tall buildings and Spanish architecture, you will be surprised by the cultural richness that the capital of Panama has to offer.
Feel free to read the recommendations and suggestions on the best spots to explore in your AZORA GUIDE.
Night in Casco Viejo (Panama City), breakfast included.
Day 2:
After the breakfast, take advantage of the day to discover the old streets of Casco Viejo and immerse yourself in the Panamanian culture. Find all our recommendations about what to do and where to eat in your AZORA GUIDE. If you want, we can organize a guided tour of the Panama Canal or Panama surroundings. Feel free to have a look at the tours in Panama City and ask us for more information.
Night in Casco Viejo (Panama City), breakfast included.



Day 3:
On the way to paradise! Arrive at the archipelago of San Blas, and settle into your bungalow. It’s time to disconnect and enjoy a beautiful panoramic view. A lazy day to recharge your batteries and discover this magical place.
Full pension with round trip transportation and San Blas Archipelago tour included.
Night in a bungalow on the beach in San Blas Archipelago.
Day 4:
After the breakfast, take place on the boat and discover several other islands of the paradisiac archipelago, that will stay in your mind for a long time! Take time to relax in the natural swimming pool and enjoy an amazing fresh lunch before heading back to the land around 3:30pm. Take the road until your next out-of-time destination: Bayano Lake!



When arrived in the meeting point, enjoy a 20min boat-ride until the Eco-Lodge in the middle of the lake. Settle in your private bungalow, just in time to enjoy a beautiful sunset.
Full pension, Bayano Caves & Tiger River tour and private jacuzzi included. You will find more details in your travel plan and AZORA GUIDE.
Night in comfortable bungalow with Bayano Lake or River view. All meals included.
Day 5:
After a local breakfast on your private terrace, discover the amazing Bayano caves and the Tiger river accompanied by your local certified guide. Enjoy an amazing walk to discover the beauty of the caves and its habitants (crocodiles, bats, snakes…). But don’t worry, it’s all safe and we’re sure you’ll enjoy it! After this unforgettable walk, take place in the kayak at your disposal and follow the guide on the Tiger River, the landscapes are amazing! Regarding the level of the water, you may have the chance to go until the “natural swimming pool” of the Tiger River.
Night in comfortable bungalow with Bayano Lake or River view. All meals included.



Day 6:
After spending the morning enjoying the facilities of the Lodge, enjoy a local lunch and get back to the road to head to Anton Valley. Whether you are traveling with certified bus transfers or a rental car, you will have around 3:30 hours before arriving in a green paradise. Settle in your hotel and enjoy a walk in the village.
Night in Valle de Antón in a beautiful room with garden view, breakfasts included.
Day 7 & 8:
Lots of activities are waiting for you in Valle de Antón! Take your AZORA GUIDE and discover our favorites to spend an unforgettable day.
Night in Valle de Antón in a beautiful room with garden view, breakfasts included.



Day 9:
We recommand to enjoy at least one sunrise in Valle de Antón before heading to Santa Catalina. Get our favorites in your AZORA GUIDE. After 4 hours of transfer or driving, you will arrive in a small place where you will find the beach and a unique underwater life to discover.
Night in Santa Catalina, breakfast included.
Day 10:
Enjoy a day tour to discover the underwater life around the Coiba island. After 45min of boat ride, discover the beauty of the several islands and swim / snorkel with sharks, turtles, numerous crazy fishes… If you prefer to dive instead, diving tours are in options and highly recommended as well! Feel free to get in touch with us to discuss the different options.
Night in Santa Catalina, breakfast and Coiba Island tour included.



Day 11:
Take the road after the breakfast to reach another small yet beautiful spot on the Pacific coast: Boca Chica. After 3 hours of transfer or driving, arrive in a heavenly place for the two next nights. Some farniente awaits for you in this magical hidden jewel of the Pacific coast of Panama… Also, we strongly recommend to do the optional 3 islas hopping tour if you want to check out a bit more of the archipelago. So feel free to let us know which tours you would like to add or remove from your journey!
Night in a Villa in Boca Chica, breakfast included.
Day 12:
Enjoy an amazing optional day tour after the breakfast or chill out by the pool and walk around the beautiful domain surrounded by a breathtaking landscape. As mentioned above, the optional 3 islands tour is available: Discover the “Three islands” of Boca Chica and dive into wonderful landscapes between jungle and lost islands. A day to remember between snorkeling, laying on the beach and living the “island vibe”. Find all our recommendations on your AZORA GUIDE for other wonderful beaches and amazing places to discover here.
Night in a Villa in Boca Chica, breakfast included.



Day 13 & 14:
Enjoy your breakfast and the facilities of your beautiful hotel before taking the road to Boquete. After 1 hour and a half, arrive in a charming mountain atmosphere. Feel free to explore and discover this completely different mountain landscape area of Boquete while staying there. At the program: hikes, treks, wild spa and nature! All our best (free) tips about what to do here will be in your AZORA GUIDE. If you wish adventure and adrenalin, you found the right place to do zipline and canopee (book with us in advance)!
Nights in Boquete, breakfasts incuded.



Day 15 & 16:
Arrive at the archipelago of Bocas del Toro, and settle into your hotel on Bastimentos Island. It’s time to disconnect and enjoy a beautiful panoramic view of the unique Red Frog Beach.
On the menu: paradise beach, turquoise water and fish… A lazy day to recharge your batteries between tropical forest and white sand. We also advise you to take advantage of your presence on the Bastimentos Island to discover the village “Old Bank”. This is where the Afro-Caribbean community of Bocas del Toro lives, the visit of the village is definitely worth it.
You will have all the informations on the flights and travel durations on your travel plan and AZORA GUIDE. We are also here to assist you whenever you need, so feel free to contact us.
Nights in Bastimentos Island (Bocas del Toro), breakfasts included.



Day 17:
Ready to discover another landscape of Bocas? Go to the heart of Bocas Town. Take advantage of your hotel’s great facilities and discover the vibrant atmosphere of the town. If not already done in the previous days, we advise you to spend the afternoon on the island opposite: Carenero. At only 1min of taxi-boat (1$ per person the way outward journey), you will arrive on a splendid small piece of land. Here, you can walk all around the island in about 1 hour. You’ll find great spots to lounge by the clear water. Great restaurants are at your disposal, see our suggestions in your AZORA GUIDE.
Night in the center of Bocas Town (Bocas del Toro), breakfast included.
Day 18:
Departure at 9:30am from the hotel, direction the reserve of Bahia Honda where you can observe dolphins and sloths. You will take advantage of the journey to the island of Zapatilla to snorkel, observe the corals and many fish. Grab your local lunch and sail with your certified guide to Zapatilla – a real “Robinson Crusoe” landscape and adventure. Enjoy a few hours on the uninhabited island and swim in the clear water… A real pleasure for the eyes.
Night in the center of Bocas Town (Bocas del Toro), breakfast and Zapatilla island tour included.



Day 19:
Take the morning to walk around the center of Bocas and enjoy the hotel facilities a last time before heading back to Panama City. You will have time to enjoy the vibrant capital of Panama and its narrow architectural streets on the afternoon.
Night in Casco Viejo (Panama City), breakfast included.
Day 20:
After your last night in Panama City, it’s unfortunately time to get back home. Our partner will pick you up at the hotel to get you to the airport. Have safe flight back!
Pricing
We suggest you two options for the PANACEA circuit. Choosing bus transfers will allow you to enjoy a comfortable and smooth journey, while choosing the rental car option will give you more autonomy and flexibility on your itinerary.
PANACEA WITH BUS TRANSFERS
20 DAYS / 19 NIGHTS
INCLUDED
✓ Private airport pick-up & drop-off
✓ Accomodations & breakfasts
✓ Complete pension during your stay in San Blas and Bayano Lake
✓ Bus transfers between each location (accredited tourists bus, pick-up and drop-off at your hotel)
✓ San Blas Archipelago tour
✓ Bayano Caves & Tiger River tour
✓ Coiba Island tour
✓ Transfer by taxi-boat from Bocas Town to your hotel in Bastimentos Island on Day 15
✓ Transfer by taxi-boat from Bastimentos Island to your hotel in Bocas Town on Day 17
✓ Zapatilla Island tour
✓ National flight from Bocas del Toro to Panama City on Day 19
✓ Transfer by taxi from the airport in Panama City to your hotel in Casco Viejo (Panama City) on Day 19
✓ AZORA GUIDE
✓ Follow-up & assistance
NOT INCLUDED
✗ International flight: check out our airline comparator to find the best flight options
Feel free to reach out if you need any assistance for booking your international flights.
✗ Optional 3 islands tour in Boca Chica
✗ Lunch & dinner when not in complete pension
✗ Tips & personal expenses
*The standard price is calculated for double occupation (2 persons). The price may evolve depending on the number of people, the season, the availabilities at the selected hotels and the duration of the stay.
PANACEA WITH RENTAL CAR
20 DAYS / 19 NIGHTS
INCLUDED
✓ Private airport pick-up & drop-off
✓ Accomodations & breakfasts
✓ Complete pension during your stay in San Blas and Bayano Lake
✓ Rental car with full cover from Day 2 to Day 14
✓ San Blas Archipelago tour
✓ Bayano Caves & Tiger River tour
✓ Coiba Island tour
✓ Bus transfer from Boquete to Bocas del Toro (Bocas Town) on Day 15
✓ Transfer by taxi-boat from Bocas Town to your hotel in Bastimentos Island on Day 15
✓ Transfer by taxi-boat from Bastimentos Island to your hotel in Bocas Town on Day 17
✓ Zapatilla Island tour
✓ National flight from Bocas del Toro to Panama City on Day 19
✓ Transfer by taxi from the airport in Panama City to your hotel in Casco Viejo (Panama City) on Day 19
✓ AZORA GUIDE
✓ Follow-up & assistance
NOT INCLUDED
✗ International flight: check out our airline comparator to find the best flight options
Feel free to reach out if you need any assistance for booking your international flights.
✗ Optional 3 islands tour in Boca Chica
✗ Lunch & dinner when not in complete pension
✗ Tips & personal expenses
IMPORTANT
✓ Car rental costs (reservation and full insurance) are included in the PANACEA package price. However, please keep in mind that this cost will be payable by the customer directly to our partner upon delivery of the car
*The standard price is calculated for double occupation (2 persons). The price may evolve depending on the number of people, the season, the availabilities at the selected hotels and the duration of the stay.
Customize your trip
Discover our recommendations to personalize your stay in Panama. Select the activities and/or places you’d like to add to your itinerary, and we’ll be happy to tailor your circuit to your wishes.
Price details
Seasons in Panama
LOW
SEASON
May, June, September & October
$
The wet season brings increased rainfall and higher humidity to Panama. Tropical rain showers are frequent, but they usually occur in short bursts, leaving ample time for exploration between showers.
MEDIUM
SEASON
July, August & November
$$
This season offers lush green landscapes, vibrant flora and fauna, and reduced tourist crowds. However, outdoor activities may be affected by occasional heavy rain.
HIGH
SEASON
From December to April
$$$
During this period, Panama experiences the dry season when rainfall is minimal, and the weather is predominantly sunny and warm. It is an ideal time to do outdoor activities, visit coastal regions, and enjoy beach days.
You may also like…
GET IN TOUCH